References. The pulps were then capped with either Keflin (an antibiotic), Durelon (a polycarboxylate cement), or Dycal (a calcium hydroxide compound). Fig.10: Since the molar continued to be completely symptom-free during this period and the cold stimulus test again produced a normal positive result, it was decided, by agreement with the In this paper, the practical aspects of pulp capping and partial pulpotomy are discussed, supported by clinical cases and, In children with deep carious lesions, the tooth’s pulp can become inflamed. Direct pulp capping was performed with reference to Dianat et al. 0000006584 00000 n Submit Close. Access scientific knowledge from anywhere. 0000015604 00000 n 0000469290 00000 n Clin Orthop Relat Res., 1993; 295: 305, like growth factor I (rhIGF-I) in rat molars. Alex, G. “Direct and indirect pulp capping: A brief history, innovations, and clinical case report.” Compendium. Direct pulp capping in immature permanent teeth Authors: Dr. Gloria Saavedra-Marbán, Dr. Eugenio C. Grano de Oro-Cordero, Dr. Cristina González Aranda Introduction Direct pulp capping (DPC) is a procedure that is usually performed on children or young persons with permanent teeth that have open apices and are showing dental lesions close to 0000010636 00000 n 0000002328 00000 n 0000459573 00000 n The treatment of these pulp conditions often results in extraction or root canal therapy. The firm necrosis causes slight irritation and stimulates the pulp to defense and repair. Following mechanical exposure, pulps were randomly capped with one of the followings materials: calcium hydroxide, biodentine or 1 × 10 5 BMDSCs mL −1 + biodentine. 0000006877 00000 n This is followed by the repair process, including migration and proliferation of mesenchymal and endothelial pulp cells and formation of collagen. 0000001888 00000 n 0000444590 00000 n Description Download Jurnal Direct and Indirect Pulp Capping Comments. Thus, suppression of the phosphorylated p38 activity by low-power laser irradiation in HP cells culminates in inhibition of the increase in IL-6 induced by PGN, suggesting that low-power laser irradiation regulates intracellular signaling molecule activities to exert its anti-inflammatory effect. Since the discovery by Herman8 of the calcium hydroxide [Ca(OH) 2] method, we get a better pulp-capping agents also have been unsuccessful in stimulating pulpal repair and healing in cases of direct carious exposures.29,30 MTA is a bioactive silicate cement that has been shown to be an effective pulp-capping material in canine models and in nonhuman pri-mates.31-33 The material is … 0000003477 00000 n They should be bacteriostatic and bactericidal, Various Materials Used For Direct Pulp Capping, drawn to disinfecting agents, because it became o. for pulp inflammation - but these agents were cytotoxic. The pulps of 40 permanent teeth of two monkeys were mechanically exposed and contaminated with adjacent saliva or plaque for 3 to 5 1/2 hours. The indications, clinical factors, materials and treatment procedures are considered along with the expected prognosis. A density of energy of 10(3) J/cm2 order applied to the pulp beads to its partial necrosis, to various inflammatory aspects (vascular, cellular, tissular) and to a quasi-constant regeneration of by a neo-dentin bridge of 200 micron at 1 month. 4. 0000021047 00000 n 0000420122 00000 n 0000005969 00000 n They should maintain pulp, forces. JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH, Revista de la Asociación Odontológica de Costa Rica. prior to placing a restoration is termed as a direct pulp capping. It is acknowledged that vital primary pulp tissue is capable of healing without resorting to comple … apatite and secondary dentin bridge formation. stimulated a more regular reparative dentin bridge. [2] A- conservative Treatment-Which aims at maintaining pulp vitality, include 1. Microscopic study after 30 and 90 days revealed considerable success in teeth treated with a mixture of vancomycin and calcium hydroxide, or with calcium hydroxide and methyl cellulose. The response of the dentin–pulp complex in rat teeth was investigated after direct capping with biodentine with or without bone marrow‐derived stem cells (BMDSCs). were the first to evaluate, have reported high success rates, which ranged from 93%, Another study of indirect pulp capping on rat molars concluded. laser irradiation stimulated mineralization in dental pulp cells. mulatta et fascicularis) stimulate in dentino-pulpal tissue morphological phenomenon, studied after 5 days, 1 and 3 months by microscopy and microradiography. Since insufficient or inappropriate diagnoses were made before treatment, even necrotic pulps. The tooth is restored with a material that seals the tooth from microleakage.7 J Dent Res., 1985; 64: 541, hybridization. 0000435290 00000 n A # 1/2 round bur (Morita, Tokyo, Japan) was used to form a cavity in the occlusal mesial surface on the maxillary first molar, and dental pulp was exposed with an explorer (YDM). tissue necrosis and significant absence of pulp inflammation. Caplan DJ, Cai J, Yin G, White BA. 0000010105 00000 n 0000018872 00000 n 0000468494 00000 n Vital pulp therapy procedures are material can decrease the rate of healing and bridge still practiced and taught in dental schools as formation. JDR, 1971; monkeys with threeagents. trailer << /Size 124 /Info 34 0 R /Root 48 0 R /Prev 665730 /ID[<23be16c9ef8a73d32b8a7bb7f9f47d07>] >> startxref 0 %%EOF 48 0 obj << /Type /Catalog /Pages 36 0 R /Metadata 35 0 R /JT 46 0 R /PageLabels 33 0 R >> endobj 122 0 obj << /S 60 /L 268 /Filter /FlateDecode /Length 123 0 R >> stream weeks, inflammatory changes in the pulp. dentine bridges formed were better than those formed by calcium hydroxide alone. In reviewing the various studies concerning the direct pulp capping procedure in primary teeth, using rigid criteria for case selection and procedure appears to insure a significant amount of success. tissue. has been greatly enhanced with the introduction of various pulp capping materials. %PDF-1.3 %���� 0000456895 00000 n It includes the application of a biomaterial directly onto the exposed pulp, followed by immediate 0000469501 00000 n Direct Pulp Capping: Here the protective dressing is placed directly above an exposed pulp. US2516438A US750631A US75063147A US2516438A US 2516438 A US2516438 A US 2516438A US 750631 A US750631 A US 750631A US 75063147 A US75063147 A US 75063147A US 2516438 A US2516438 A US 2516438A Authority US United States Prior art keywords parts eugenol capping liquid powder Prior art date 1947-05-26 Legal status (The legal status is an assumption and is not a legal … The presence of calcium ions stimulates precipitation of calcium carbonate in the wound area and thereby contributes to the initiation of mineralization. Direct pulp capping. Initially bactericidal then bacteriostatic, Does not exclusively stimulate dentinogenesis, Does not exclusively stimulate reparative dentin, May dissolve after one year with cavosurface dissolution, Marginal failure with amalgam condensation, Does not adhere to the dentin or resin restoration, Glass Ionomer (GI) / Resin-Modifed Glass Ionomer (RMGI), Patient did not present any pain or discomfort, β). Direct pulp capping is used when the pulp is visibly exposed (vital pulp … EMD is enamel matrix derivative secreted from Hertwig’s epithelial root sheath during, porcine tooth development. 0000004900 00000 n The low rate of satisfactory responses of pulps capped with Keflin, as used, precludes its use of pulp capping. 0000451066 00000 n The extracellular collagen production was significantly increased by 73% on day 2 and 38% on day 4 after laser irradiation (P < 0.05). Pulp exposed after a deep carious lesion may be treated by bioactive molecules or by differentiated pulp cells. The successes of direct pulp capping are less, decreasing to 37% after 5 years, and 13% after 10 years. DOWNLOAD PDF . Brown-Brenn staining revealed no bacterial microleakage at both time points. 0000006806 00000 n Bjorndal, L. et al. Although collagen type I gene expression was not changed by laser irradiation, HSP47 gene and protein expression was induced within 12 and 24 h, respectively. healing characterized by cell-rich fibro dentin and tertiary dentin deposition. The initial effect of calcium hydroxide applied to exposed pulp is the development of a superficial three-layer necrosis. formation. The analysis of cell activity seems able to be investigated from this method. The amounts of secreted collagen from the cells after irradiation were quantified following Sirius Red staining. 0000002557 00000 n 0000012314 00000 n This is one-step procedure and is indicated in cases where there is pinpoint exposure of the pulp due to mechanical trauma (accidents, falls or fracture) or accidental exposure of the pulp during cavity preparation or removal of dental caries. Direst pulp capping (DPC) has been literally abolished from the repertoire of endodontic procedures for primary teeth. Indirect pulp treatment. Caries Res. 0000005492 00000 n Share. Tziafas D. The future role of a molecular approach to pulp-dentinal regeneration. OBJECTIVES: a) preservation of vitality of the radicular pulp. In the present study, to elucidate the mechanism behind the anti-inflammatory effect, we examined the effects of low-power neodymium-doped yttrium-aluminium-garnet (Nd:YAG) laser irradiation on interleukin (IL)-6 expression in human pulp (HP) cells stimulated by peptidoglycan (PGN) and focused on intracellular signaling pathways. J Am Dent Assoc, 1976; 93(1): 105, pulp-capping agents. Direct pulp capping in primary teeth due to a carious exposure is not indicated but is used in permanent teeth. effect and calcific bri Fluocinolone acetonide. Each monkey received at least one dose of Procion red H-8BS vital dye. This article will provide a general discussion of direct and indirect pulp capping procedures, offering practitioners a pragmatic and science-based clinical protocol for treatment of vital pulp exposures. Watts and Paterson cautioned that anti-inflammatory compounds. These procedures are indicated for primary, immature permanent, and mature permanent teeth in children and adolescents. 0000015260 00000 n Ideal direct pulp capping materials/agents is inducing dentinogenesis similar with natural biological process to pulp. The dentin exposed to a density of energy of: 2 X 10(3) J/cm2 shows a burn, a rarefaction and a cellular degeneration, followed by a neoformation of calcified dentin, of about 300 microns thick in 3 months, due to the excitation of odontoblasts or produced by pulpal cells functioning before. J Endod, 1980; 6(7): 641, pulp capping medicine substitutes for osteodentin. 0000435444 00000 n The procedure of pulp capping relies primarily on the ability of pulpal tissue to heal. The often-repeated claim that calcium hydroxide compounds exert a persistent stimulating effect on the pulp resulting in its eventual obliteration was not supported. [1] Pulp treatment modality can be classified to 2 categories. 0000002884 00000 n 0000467995 00000 n 2010; 14(5):559–67. 0000016707 00000 n Among the goals of pulp capping are to manage bacteria, arrest caries progression, stimulate pulp cells to form new dentin, and produce a durable seal that protects the pulp complex. Cell viability was examined 24 h after laser irradiation by a modified MTT assay. 0000412667 00000 n All rights reserved. A direct pulp cap is done on permanent teeth when the removal of deep decay results in exposing the pulp. 0000002350 00000 n Dammaschke T, Leidinger J, Schafer E. Long-term evaluation of direct pulp capping-treatment outcomes over an average period of 6.1 years. RESULTS: The clinical aspect of direct pulp capping during the operation was satisfactory, and all patients were asymptomatic in the postoperative phase. to know cleaning ability of root canal with different system. A hybrid layer was seen on all walls but decreased gradually toward the area of pulp exposure. Vital pulp therapy procedures can treat the decay approximating the pulp to avoid the pulp becoming infected or being. Pulp capping procedures is often into the pulp may have direct influence on the performed when a pulpal exposure occurs due to inflammatory response. Three months after the procedure, Tooth 36 was clinically normal and tested positive for … The era of vital-pulp therapy TGF β is a potent modulator of tissue r, Cohen BD, Combe EC. Report "Jurnal Direct and Indirect Pulp Capping "Please fill this form, we will try to respond as soon as possible. 0000444549 00000 n 16. Direct pulp capping Indirect pulp capping 15. In this histological study, 19 human teeth were mechanically exposed and the pulps were capped with isobutyl cyanoacrylate. silicate particles in a hydrophilic monomer that provides significant calcium release making it. When the pulp is protected from irritation, odontoblasts differentiate, and the tissue formed assumes the appearance of dentin, i.e., the function of the pulp is normalized. 0000020370 00000 n 0000469867 00000 n 0000003099 00000 n 0000467869 00000 n J Endod, 2009; 35(3): 373, observational study. 0000005930 00000 n Embed. H�b```f``?�������A�@l6 ��q`Hx4��M� Direct capping is effective when it is carried out on a pulp exposure, revealing an initial opening of a pulp horn, and accompanied with bacterial invasion. 0000425750 00000 n A lot of specialist in the last 15 years work and pub-lish interesting result for successful application of direct pulp capping in primary dentition. 0000018177 00000 n 0000467726 00000 n IPT has been shown to be successful using stepwise caries excavation in two appointments or using partial caries excavation as a one-appointment procedure. B-Radical treatment-consisting of pulpectomy and root filling, All content in this area was uploaded by Priti D Desai on Jul 10, 2020, Dr. Priti D. Desai*, Dr. Sampurna Dutta Gupta, Dr. Saikat Chatterjee, Dr. Soumyadeep, Mondol, Dr. Pritam Sengupta and Dr. Shromi Roy Choudhury, Prof. in the Department of Consevative Dentistry and Endodontics, Guru Nanak Institute of. The exposed pulp surface was then washed with physiological saline. All of the Dycal-capped pulps showed complete bridging and no inflammation or pulp obliteration. Radiographs were of little value in determining the presence of a dentin bridge. 0000011556 00000 n The laser irradiation also increased HSP47 expression but not collagen gene expression. BMP belongs to super family transforming growth, differentiated mesenchymal cells from the. Pulp protection is the term coined by AAPD which recommends the placement of a protective base or a liner on the pulpal and axial walls of the cavity preparation to act as a protective barrier between the restorative material and the tooth. Argon Laser, Diode Laser, Erbium:Yttrium-Aluminum Garnet (Er.YAG) are widely used. Of 13 teeth capped with Keflin, only 4 responded satisfactorily. Development of new adhesive pulp capping materials. induce angiogenesis and increase neuronal cells, indicating the possible effectiveness of statin, secondry dentin formation. A p38 mitogen-activated protein kinase inhibitor, SB203580, also inhibited the increase in IL-6 messenger RNA levels. An alternative to pulpotomy, extraction, or pulpectomy for deep carious lesions where the pulp is vital is indirect pulp treatment (IPT). Protective base. 0000014867 00000 n 0000020349 00000 n 0000412530 00000 n Defined as a procedure in which the exposed vital pulp is covered with a protective dressing or base placed directly over the site of exposure in an attempt to preserve the pulp vitality. The aim of this article is to summarize and discuss various pulp capping materials. the direct pulp capping is not suitable for carious opened pulp with reversible pulpitis but recommend more investi-gations in this direction which could change the current opinion [8]. 79 Direct Pulp Capping with Bioactive Material: Biodentine Citation: K Laslami., et al.. “Direct Pulp Capping with Bioactive Material: Biodentine”. 0000004266 00000 n 0000018156 00000 n When a pinpoint mechanical exposure of the pulp is encountered during cavity preparation or follow-ing a traumatic injury, a biocompatible radiopaque base such as MTA41-44 or calcium hydroxide45 may be placed in contact with the exposed pulp tissue. 0000021688 00000 n The findings from the recent literature on pulpal cell responses to the application of calcium hydroxide to exposed pulps are described. Educational video for dental students and dentists on the Direct Pulp Capping procedure. These results suggested that carbon dioxide laser irradiation stimulated mineralization in dental pulp cells. Abstract: Among the goals of pulp capping are to manage bacteria, arrest caries progression, stimulate pulp cells to form new dentin, and produce a durable seal that protects the pulp complex. Surgically exposed, infected permanent teeth of monkeys were capped with four agents. Rat dental pulp cells were irradiated with a carbon dioxide laser at 2 W output power for 20, 40 and 60 s, and were cultured in ascorbic acid and beta-glycerophosphate containing media. Pulp treatment modality can be classified to 2 categories. The aim of this article is to summarize and discuss Direct pulp capping (DPC) treatment is used when the vital asymptomatic pulp is visibly exposed due to caries or trauma, or due to a misadventure during tooth preparation or caries removal [7]. Pulpotomy. The findings of this study support the findings in our previous study3 and further substantiate the effectiveness of Dycal as a pulp-capping agent. 0000004040 00000 n Join ResearchGate to find the people and research you need to help your work. Direct puip capping The cleaner tooth surface could also conceivably allow better adaptation of the restorative material and hence reduce microleakage (37). 0000011184 00000 n 0000468210 00000 n Int Endod J., 2009; 42(10): 940, human pulp cells. desirable option as a cell source for therapeutic applications. 0000010298 00000 n biomineralisation ability for hard tissue regeneration and also high biocompatibility. 0000015973 00000 n Direct pulp cap. Low-power laser irradiation inhibited the activity. 0000020295 00000 n Alternate slides were stained with hematoxylin ane eosin. Oper Dent, 1996; 21(1): 4, migration, proliferation, and differentiation. Alizarin Red S staining was performed 10 days after laser irradiation. (grossman) • without signs or symptoms of pulp degeneration. EC Dental Science 13.2 (2017): 75-83. J Am Dent Assoc, 2008; 139(3): 305, hydroxide (MTYA1-Ca) Int Endod J., 1999; 32(6): 475, dentinogenesis. histology, with evidence of vasodilation. In our next article, we’ll discuss the direct pulp cap procedure. In cases of direct pulp capping, a continuous hard tissue barrier determined by direct clinical ex-amination and a positive response to electric pulp tester stimulation. growth factor), IGF (insulin-like growth factor) and FGF (fibroblast growth factor). [13] and Trongkij et al. Indirect pulp capping • procedure where the deepest layer of the remaining affected carious dentin is covered with layer of biocompatible material in order to prevent pulpal exposure and further trauma to pulp. In direct capping with this paste showed no pulp degeneration and formation of protective layer It contains flavonoids, phenolics, iron, zinc and other various aromatic compounds. ���D���XN0$2�0�0`�`JepO`ka�dPU`�����t�Ѱ�iü�L��Xp>a�k`�aX��$��4JdG�F7 ��dz�"��|$�0���� 9���y�#���\,g4.`aV{u�ՠ��)6Fv.���kl�&0. Clin Oral Investig. The observed sequence of tissue reactions is that which is expected when connective tissue is wounded. It was shown that this chemical adhesive produces immediate hemostasis and permits the repair of the injured pulp. The exposed coronal pulp leads to treatment of the pulp patients at risk from bacteremia Qureshi. J Am Dent Assoc, 1994; 125(7): 823. vancomycin and calcium hydroxide. The amount of mineralization after 10 days of irradiation at 2 W for 40 s was significantly increased in comparison to the other conditions (P < 0.05). This procedure is a noninvasive, comparatively simple, and inexpensive treatment, with the overall aim to preserve healthy pulp tissue. Current direct pulp capping is the reaction of dental pulp to the chemical stimulation. Emphasis has shifted from the “doomed” organ concept of an exposed pulp to one of hope and recovery. 0000006898 00000 n more than twice that of the calcium hydroxide treated control teeth. Dent, Yoshimine Y, Maeda K. Histologic evaluation of tetracalcium phosphate-based cement as. Adv Dent Res., 2001; 15: 108, direct pulp capping with growth factors. Traumatic inflammation due to application of CO2 laser beam on teeth (dentin and pulp) of Beagle dogs and Macaca Monkeys, stimulate in dentino-pulpal tissue morphological phenomena studied after 5 days, 1, and 3 months by microscopy and microradiography. Serial, decalcified, 7 mum-thick paraffin sections were prepared. However, It has excellent antibacterial properties and low cytotoxicity. 0000021827 00000 n 0000420210 00000 n This article will provide a general discussion of direct and indirect pulp capping procedures, offering practitioners a pragmatic and science-based clinical protocol for treatment of vital pulp exposures. 2. The choice of an appropriate restorative material to reduce bacterial microleakage can increase the success of direct pulp capping (19, 38-40). Varnish and then amalgam were inserted. Pitt Ford et al. It is an important. If this lesion is not treated properly, the caries can approximate the pulp resulting in pain and infection. 0000018851 00000 n 2004; 38(3):314–20. calcium hydroxide control groups showed significantly better pulpal healing. weeks after direct pulp capping. treated with pulpotomy. Email. 0000468597 00000 n In conclusion, MTA has a higher clinical success rate for direct pulp capping 7. 3. Traumatic inflammation due to application of CO2 laser radiation (lambda = 10.6 microns) on the dentin and on pulp of 342 teeth of 8 dogs (Beagle) and of 6 monkeys (Macaca sp. Direct pulp capping and the formation of reparative dentin The treatment of a pulp exposure involves direct capping. March 2018: 39 (3): 182-189. [14]. b) relief of pain in patients with acute pulpagia. 0000469764 00000 n 0000468856 00000 n 47 0 obj << /Linearized 1 /O 49 /H [ 1993 357 ] /L 666798 /E 470556 /N 4 /T 665740 >> endobj xref 47 77 0000000016 00000 n Description. To examine the effect of carbon dioxide laser irradiation on mineralization in dental pulp cells. Gurunanak Institute of Dental Sciences & Research, Carbon dioxide laser irradiation stimulates mineralization in rat dental pulp cells, Neodymium-doped Yttrium-Aluminium-Garnet Laser Irradiation Abolishes the Increase in Interleukin-6 Levels Caused by Peptidoglycan through the p38 Mitogen-activated Protein Kinase Pathway in Human Pulp Cells, Long-term study of pulp capping in monkeys with three agents, Experimental research on the preparation of dentin-pulp tissue of teeth exposed to CO2 laser beams in dogs and macaques (Macaca mulatta and Macaca fascicularis), Latest treatment in dentistry by means of the CO2 laser beam, Dental Pulp Exposed to the CO2 Laser Beam, Effects of Calcium Hydroxide-containing Pulp-capping Agents on Pulp Cell Migration, Proliferation, and Differentiation, Human Pulp Capping with Isobutyl Cyanoacrylate, Treatment of Pulps of Monkeys with Vancomycin and Calcium Hydroxide, Reconstituted antigen-poor collagen preparations as potential pulp-capping agents, compare multifile system versus single file system for debris and smear layer formation during root canal cleaning and shaping, Recent Advances in Pulp Capping Materials: An Overview, Vital Pulp Treatment: clinical considerations, Indirect Pulp Treatment, Direct Pulp Capping, and Stepwise Caries Excavation.

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